1 Studies estimate that 75 percent of Americans do not meet the recommended dietary allowance of magneisum, 2 which has raised concern about the health effects of magnesium deficiency. It is distributed approximately one half in the bone and one half in the muscle and other soft tissues less than one percent is in the blood. Magnesium is the fourth most abundant essential mineral in the body. Food sources of magnesium include green leafy vegetables, nuts, legumes, and whole grains. Because magnesium is excreted renally, it should be used with caution in patients with kidney disease. Although it is safe in selected patients at appropriate dosages, magnesium may cause adverse effects or death at high dosages. The use of magnesium for constipation and dyspepsia are accepted as standard care despite limited evidence. Other areas that have shown promising results include lowering the risk of metabolic syndrome, improving glucose and insulin metabolism, relieving symptoms of dysmenorrhea, and alleviating leg cramps in women who are pregnant. Studies have shown the effectiveness of magnesium in eclampsia and preeclampsia, arrhythmia, severe asthma, and migraine. This has led to an increased awareness of proper magnesium intake and its potential therapeutic role in a number of medical conditions. Research has shown that the mineral content of magnesium in food sources is declining, and that magnesium depletion has been detected in persons with some chronic diseases. Magnesium is an essential mineral for optimal metabolic function.
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